Sede ufficiale: VIA LUCA GHINI 13, 56126 PISA
Email: stefano.landi@unipi.it
Telefono: 050 2211528
Sito web: www.stefanolandi.eu
Profilo
Ruolo: Professore Ordinario
Struttura: Dipartimento di Biologia
Settore scientifico-disciplinare: Genetica BIOS-14/A
Curriculum of the scientific and teaching activity of Dr. Stefano Landi
Courses and education:
• 1981/82 –1985/86: High School (Diploma di Maturitá Scientifica)
• 1986/87 –1990/91: Master degree in Biological Sciences (Laurea in Scienze Biologiche)
University of Pisa, Facolty of Sciences
Final score: 110/110 + laudem
• 1991/92: Post-lauream training and subscription to the professional register of the biologists.
• 1991/92 – 1993/94: Ph D. (1) in Genetics
University of Ferrara
• November 1994 October 1996: Post-doctoral fellowship
October 1996 - March 1997: Fellowship (Finnish Institute of Occupational Health, Helsinki, Finland)
• Avril 1997 - Avril 1999: Fellowships
University of Pisa
• February 1998 – February 2000: Post Doctoral position, Associateship Award
US Environmental Protection Agency (USEPA), Research Triangle Park, North Carolina, USA.
Tutor: Dr. David DeMarini, Ph. D.
• February – November 2000: Post Doctoral position, Special Training Award
International Agency for Research on Cancer (IARC).
Tutor: Dr. Federico Canzian
• December 2000 – November 2002 : Post-doctoral position, Marie-Curie Individual Fellowship (HPMFCT-2000-00483).
IARC, Lione, Francia.
Tutor: Dr. Federico Canzian
• November 1999 – July 2001 : Specializing school in Applied Genetics
University of Pisa.
Final score: 110/110 + laudem
• 1/5/2001 – 1/5/2004: Short-term position of Scientist Researcher. Genetics, University of Pisa.
• Since 1/5/2004 – 31/12/2011: Permanent position of Scientist Researcher. Genetics, University of Pisa.
• 1/1/2012 - 31/12/2015: Associate professor of Genetics (SSD BIO/18). University of Pisa.
• 1/1/2016 - present: Full professor of Genetics (SSD BIO/18). University of Pisa.
Research grants:
1) Marie-Curie Reintegration Grant della Commissione Europea (MERG-CT-2004-506373)
2) Contract with “Fondazione Buzzi” Prot. 180 del 2/7/2004
3) AIRC- Regional Grants. N. 1082 del 2005-2007. Co-investigator.
4) AIRC- Principal Investigator Grant. N. 1714 del 2005-2006
5) NCI (NIH-USA) Grant code R03CA115062, anno 2006-2008. Principal Investigator. Small grants in cancer epidemiology.
6) AIRC- Principal Investigator Grant. N. 4601 del 2008-2011
7) Donation for research from “Fondazione Buzzi” Prot. 156 del 25/02/2010 (cod. P22)
8) Italian Ministry of Research, PRIN grant 2009-2012
9) 2004-2016. Regular budget, University of Pisa
10) ITT, Tuscany Research Institute of Research on Cancer (2014-2017). Project title: “Variation in miRNA genes and in miRNA binding sites of DNA repair genes as diagnostic, predictive and prognostic factors of colorectal cancer”
11) PRA projects program (University of Pisa). PRA_2016_21, year 2015-2016
12) 05/2017-2020 Fondazione Pisa. Diatec-Meso. PI research grant system.
13) AIRC, Italian Association for Research on Cancer (2019-), 5 years Investigator Grant
Teaching activity:
• Years 2002-2003: “Genetics II” (for the Master degree in Biological Science, University of Pisa, 5 credits).
• Years 2003-2004: “Genetic Engineering” (for the Bachelor degree in Biological and Molecular Biology, University of Pisa, 6 credits).
• Years 2004-2010: “Structural and Functional Genomics” (for the Master degree in Biomolecular sciences and technologies, University of Pisa, 5 credits).
• Years 2009-2016: “Genetics and Genomics analyses” (for the Master degree in Cellular and Molecular Biology, University of Pisa, 6 credits).
• Years 2011-2014: “General Biology” (for the Bachelor degree in Natural Sciences, University of Pisa, 6 credits)
• Years 2015-present: “Genetics” (for the Bachelor degree in Biological Sciences, University of Pisa, 9 credits)
• Year 2016-present: “Neurogenomics” (for the Master Degree in Neurosciences, University of Pisa, 3 credits)
• Year 2018: “Genetics” (for the Bachelor degree in Biotechnologies, University of Pisa, 6 credits)
Courses and education:
• 1981/82 –1985/86: High School (Diploma di Maturitá Scientifica)
• 1986/87 –1990/91: Master degree in Biological Sciences (Laurea in Scienze Biologiche)
University of Pisa, Facolty of Sciences
Final score: 110/110 + laudem
• 1991/92: Post-lauream training and subscription to the professional register of the biologists.
• 1991/92 – 1993/94: Ph D. (1) in Genetics
University of Ferrara
• November 1994 October 1996: Post-doctoral fellowship
October 1996 - March 1997: Fellowship (Finnish Institute of Occupational Health, Helsinki, Finland)
• Avril 1997 - Avril 1999: Fellowships
University of Pisa
• February 1998 – February 2000: Post Doctoral position, Associateship Award
US Environmental Protection Agency (USEPA), Research Triangle Park, North Carolina, USA.
Tutor: Dr. David DeMarini, Ph. D.
• February – November 2000: Post Doctoral position, Special Training Award
International Agency for Research on Cancer (IARC).
Tutor: Dr. Federico Canzian
• December 2000 – November 2002 : Post-doctoral position, Marie-Curie Individual Fellowship (HPMFCT-2000-00483).
IARC, Lione, Francia.
Tutor: Dr. Federico Canzian
• November 1999 – July 2001 : Specializing school in Applied Genetics
University of Pisa.
Final score: 110/110 + laudem
• 1/5/2001 – 1/5/2004: Short-term position of Scientist Researcher. Genetics, University of Pisa.
• Since 1/5/2004 – 31/12/2011: Permanent position of Scientist Researcher. Genetics, University of Pisa.
• 1/1/2012 - 31/12/2015: Associate professor of Genetics (SSD BIO/18). University of Pisa.
• 1/1/2016 - present: Full professor of Genetics (SSD BIO/18). University of Pisa.
Research grants:
1) Marie-Curie Reintegration Grant della Commissione Europea (MERG-CT-2004-506373)
2) Contract with “Fondazione Buzzi” Prot. 180 del 2/7/2004
3) AIRC- Regional Grants. N. 1082 del 2005-2007. Co-investigator.
4) AIRC- Principal Investigator Grant. N. 1714 del 2005-2006
5) NCI (NIH-USA) Grant code R03CA115062, anno 2006-2008. Principal Investigator. Small grants in cancer epidemiology.
6) AIRC- Principal Investigator Grant. N. 4601 del 2008-2011
7) Donation for research from “Fondazione Buzzi” Prot. 156 del 25/02/2010 (cod. P22)
8) Italian Ministry of Research, PRIN grant 2009-2012
9) 2004-2016. Regular budget, University of Pisa
10) ITT, Tuscany Research Institute of Research on Cancer (2014-2017). Project title: “Variation in miRNA genes and in miRNA binding sites of DNA repair genes as diagnostic, predictive and prognostic factors of colorectal cancer”
11) PRA projects program (University of Pisa). PRA_2016_21, year 2015-2016
12) 05/2017-2020 Fondazione Pisa. Diatec-Meso. PI research grant system.
13) AIRC, Italian Association for Research on Cancer (2019-), 5 years Investigator Grant
Teaching activity:
• Years 2002-2003: “Genetics II” (for the Master degree in Biological Science, University of Pisa, 5 credits).
• Years 2003-2004: “Genetic Engineering” (for the Bachelor degree in Biological and Molecular Biology, University of Pisa, 6 credits).
• Years 2004-2010: “Structural and Functional Genomics” (for the Master degree in Biomolecular sciences and technologies, University of Pisa, 5 credits).
• Years 2009-2016: “Genetics and Genomics analyses” (for the Master degree in Cellular and Molecular Biology, University of Pisa, 6 credits).
• Years 2011-2014: “General Biology” (for the Bachelor degree in Natural Sciences, University of Pisa, 6 credits)
• Years 2015-present: “Genetics” (for the Bachelor degree in Biological Sciences, University of Pisa, 9 credits)
• Year 2016-present: “Neurogenomics” (for the Master Degree in Neurosciences, University of Pisa, 3 credits)
• Year 2018: “Genetics” (for the Bachelor degree in Biotechnologies, University of Pisa, 6 credits)
Didattica
Attività didattica
Incarichi di responsabilità didattica di moduli/insegnamenti
- Biology (cod. EE067) per Corso Singolo in Foundation course science
- Genetica (cod. 082EE) per Laurea in Scienze biologiche
- Genetica (modulo dell'insegnamento biologia generale cod. 311ee) per Laurea in Scienze naturali e ambientali
Ricevimento
Modalità: L'orario di ricevimento e' libero previo appuntamento via e-mail. Verificare anche sul sito www.stefanolandi.eu
Luogo: Via Derna, 1 (secondo piano).
Orario: L'orario di ricevimento e' libero previo appuntamento via e-mail.
Ricerca
Pubblicazioni
- Transcriptomic Profiling of the Tumor Microenvironment in High-Grade Serous Carcinoma: A Pilot Study of Morphologic and Molecular Distinctions Between Classic and SET Patterns (Giannini, Riccardo; Bartoli, Francesco; Ieso, Katia De; Camacci, Tiziano; Bertolucci, Andrea; Piccini, Lorenzo; Rreka, Erion; Volterrani, Duccio; Gemignani, Federica; Landi, Stefano; Ugolini, Clara; Lippolis, Piero Vincenzo; Faviana, Pinuccia - 2025 - 1.1 Articolo in rivista)
- Body Mass Index and Sporadic Medullary Thyroid Cancer: Insights from a Large Series (Prete, Alessandro; Gambale, Carla; Bottici, Valeria; Cappagli, Virginia; Aringhieri, Giacomo; Puccini, Marco; Landi, Stefano; Torregrossa, Liborio; Santini, Ferruccio; Matrone, Antonio; Elisei, Rossella - 2025 - 1.1 Articolo in rivista)
- BAG2, MAD2L1, and MDK are cancer-driver genes and candidate targets for novel therapies in malignant pleural mesothelioma (Bisceglia, Luisa; Morani, Federica; Guerrieri, Lara; Santoni-Rugiu, Eric; Çakilkaya, Pinar; Scatena, Cristian; Scarpitta, Rosa; Engelholm, Lars H.; Behrendt, Niels; Gemignani, Federica; Landi, Stefano - 2024 - 1.1 Articolo in rivista)
- Comparative analysis of genetic variants in pleural fluids and solid tissue biopsies of pleural mesothelioma patients: Implications for molecular heterogeneity assessment (Silvestri, Roberto; Rea, Filomena; Vitiello, Marianna; Moretti, Gabriele; Aprile, Vittorio; Lucchi, Marco; Aretini, Paolo; Mazzanti, CHIARA MARIA; Landi, Stefano; Gemignani, Federica - 2024 - 1.1 Articolo in rivista)
- Polymorphism Pro64His within galectin-3 has functional consequences at proteome level in thyroid cells (Silvestri, Roberto; Zallocco, Lorenzo; Corrado, Alda; Ronci, Maurizio; Aceto, Romina; Ricci, Benedetta; Cipollini, Monica; Dell'Anno, Irene; De Simone, Chiara; De Marco, Giuseppina; Ferrarini, Eleonora; Beghelli, Daniela; Mazzoni, Maria Rosa; Lucacchini, Antonio; Gemignani, Federica; Giusti, Laura; Landi, Stefano - 2024 - 1.1 Articolo in rivista)
- Polymorphisms in transcription factor binding sites and enhancer regions and pancreatic ductal adenocarcinoma risk (Ünal, Pelin; Lu, Ye; Bueno-de-Mesquita, Bas; van Eijck, Casper H. J.; Talar-Wojnarowska, Renata; Szentesi, Andrea; Gazouli, Maria; Kreivenaite, Edita; Tavano, Francesca; Malecka-Wojciesko, Ewa; Eross, Bálint; Oliverius, Martin; Bunduc, Stefania; Nóbrega Aoki, Mateus; Vodickova, Ludmila; Boggi, Ugo; Giaccherini, Matteo; Kondrackiene, Jurate; Chammas, Roger; Palmieri, Orazio; Theodoropoulos, George E.; Bijlsma, Maarten F.; Basso, Daniela; Mohelnikova-Duchonova, Beatrice; Soucek, Pavel; Izbicki, Jakob R.; Kiudelis, Vytautas; Vanella, Giuseppe; Arcidiacono, Paolo Giorgio; Wlodarczyk, Barbara; Hackert, Thilo; Schöttker, Ben; Uzunoglu, Faik G.; Bambi, Franco; Goetz, Mara; Hlavac, Viktor; Brenner, Hermann; Perri, Francesco; Carrara, Silvia; Landi, Stefano; Hegyi, Péter; Dijk, Frederike; Maiello, Evaristo; Capretti, Giovanni; Testoni, Sabrina Gloria Giulia; Petrone, Maria Chiara; Stocker, Hannah; Ermini, Stefano; Archibugi, Livia; Gentiluomo, Manuel; Cavestro, Giulia Martina; Pezzilli, Raffaele; Di Franco, Gregorio; Milanetto, Anna Caterina; Sperti, Cosimo; Neoptolemos, John P.; Morelli, Luca; Vokacova, Klara; Pasquali, Claudio; Lawlor, Rita T.; Bazzocchi, Francesca; Kupcinskas, Juozas; Capurso, Gabriele; Campa, Daniele; Canzian, Federico - 2024 - 1.1 Articolo in rivista)
- Strategies for single base gene editing in an immortalized human cell line by CRISPR/Cas9 technology (Corrado, Alda; Aceto, Romina; Miglietta, Simona; Silvestri, Roberto; Dell'Anno, Irene; Lepori, Irene; Ricci, Benedetta; Romei, Cristina; Giovannoni, Roberto; Poliseno, Laura; Evangelista, Monica; Vitiello, Marianna; Cipollini, Monica; Elisei, Rossella; Landi, Stefano; Gemignani, Federica - 2024 - 1.1 Articolo in rivista)
- Identification of novel genetic loci for risk of multiple myeloma by functional annotation (Macauda, Angelica; Briem, Klara; Clay-Gilmour, Alyssa; Cozen, Wendy; Försti, Asta; Giaccherini, Matteo; Corradi, Chiara; Sainz, Juan; Niazi, Yasmeen; Ter Horst, Rob; Li, Yang; Netea, Mihai G; Vogel, Ulla; Hemminki, Kari; Slager, Susan L; Varkonyi, Judit; Andersen, Vibeke; Iskierka-Jazdzewska, Elzbieta; Mártinez-Lopez, Joaquin; Zaucha, Jan; Camp, Nicola J; Rajkumar, S Vincent; Druzd-Sitek, Agnieszka; Bhatti, Parveen; Chanock, Stephen J; Kumar, Shaji K; Subocz, Edyta; Mazur, Grzegorz; Landi, Stefano; Machiela, Mitchell J; Jerez, Andrés; Norman, Aaron D; Hildebrandt, Michelle A T; Kadar, Katalin; Berndt, Sonja I; Ziv, Elad; Buda, Gabriele; Nagler, Arnon; Dumontet, Charles; Razny, Malgorzata; Watek, Marzena; Butrym, Aleksandra; Grzasko, Norbert; Dudzinski, Marek; Rybicka-Ramos, Malwina; Matera, Eva-Laure; García-Sanz, Ramón; Goldschmidt, Hartmut; Jamroziak, Krzysztof; Jurczyszyn, Artur; Clavero, Esther; Giles, Graham G; Pelosini, Matteo; Zawirska, Daria; Kruszewski, Marcin; Marques, Herlander; Haastrup, Eva; Sánchez-Maldonado, José Manuel; Bertsch, Uta; Rymko, Marcin; Raab, Marc-Steffen; Brown, Elizabeth E; Hofmann, Jonathan N; Vachon, Celine; Campa, Daniele; Canzian, Federico - 2023 - 1.1 Articolo in rivista)
- A scan of all coding region variants of the human genome, identifies 13q12.2-rs9579139 and 15q24.1-rs2277598 as novel risk loci for pancreatic ductal adenocarcinoma (Giaccherini, Matteo; Gori, Leonardo; Gentiluomo, Manuel; Farinella, Riccardo; Cervena, Klara; Skieceviciene, Jurgita; Dijk, Frederike; Capurso, Gabriele; Vezakis, Antonis; Archibugi, Livia; Chammas, Roger; Hussein, Tamás; Tavano, Francesca; Hegyi, Péter; Lovecek, Martin; Izbicki, Jakob R; Brenner, Hermann; Mohelnikova-Duchonova, Beatrice; Dell’Anna, Giuseppe; Kupcinskas, Juozas; Ermini, Stefano; Aoki, Mateus Nóbrega; Neoptolemos, John P; Gazouli, Maria; Pasquali, Claudio; Pezzilli, Raffaele; Talar-Wojnarowska, Renata; Oliverius, Martin; Al-Saeedi, Mohammed; Lucchesi, Maurizio; Furbetta, Niccolò; Carrara, Silvia; van Eijck, Casper H J; Maleckas, Almantas; Milanetto, Anna Caterina; Lawlor, Rita T; Schöttker, Ben; Boggi, Ugo; Morelli, Luca; Ginocchi, Laura; Ponz de Leon Pisani, Ruggero; Sperti, Cosimo; Zerbi, Alessandro; Arcidiacono, Paolo Giorgio; Uzunoglu, Faik G; Bunduc, Stefania; Holleczek, Bernd; Gioffreda, Domenica; Malecka-Wojciesko, Ewa; Kiudelis, Mindaugas; Szentesi, Andrea; van Laarhoven, Hanneke W M; Soucek, Pavel; Götz, Mara; Eross, Bálint; Cavestro, Giulia Martina; Basso, Daniela; Perri, Francesco; Landi, Stefano; Canzian, Federico; Campa, Daniele - 2023 - 1.1 Articolo in rivista)
- Do GWAS-Identified Risk Variants for Chronic Lymphocytic Leukemia Influence Overall Patient Survival and Disease Progression? (José Cabrera-Serrano, Antonio; Manuel Sánchez-Maldonado, José; ter Horst, Rob; Macauda, Angelica; García-Martín, Paloma; Benavente, Yolanda; Landi, Stefano; Clay-Gilmour, Alyssa; Niazi, Yasmeen; Espinet, Blanca; José Rodríguez-Sevilla, Juan; María Pérez, Eva; Maffei, Rossana; Blanco, Gonzalo; Giaccherini, Matteo; Cerhan, James R.; Marasca, Roberto; Ángel López-Nevot, Miguel; Chen-Liang, Tzu; Thomsen, Hauke; Gámez, Irene; Campa, Daniele; Moreno, Víctor; de Sanjosé, Silvia; Marcos-Gragera, Rafael; García-Álvarez, María; Dierssen-Sotos, Trinidad; Jerez, Andrés; Butrym, Aleksandra; Norman, Aaron D.; Luppi, Mario; Slager, Susan L.; Hemminki, Kari; Li, Yang; Berndt, Sonja I.; Casabonne, Delphine; Alcoceba, Miguel; Puiggros, Anna; Netea, Mihai G.; Försti, Asta; Canzian, Federico; Sainz, Juan - 2023 - 1.1 Articolo in rivista)