ALESSANDRA SALVETTI
Date and Place of Birth: October 29, 1969, Pisa (Italy)
Research Interests: -Molecular and cellular mechanisms of stem cell maintenance, homing and differentiation.
-Identification of potential target for cancer therapy
Education and qualification:
Since 2008-date: Assistant professor of cell biology and general genetics, University of Pisa, Department of Clinical and Experimental Medicine
Since 2007-date: Member of international postgraduate assessment committees
July 2000- 2008: Researcher at University of Pisa, Lecturer in Biology and Genetics.
May 1998: Phd degree in Molecular Biology and Biophysics of the Cell and the Development, University of Pisa
Jen.-July. 1997: Fellowship offered by European Molecular Biology Organization (EMBO) for a position of Guest Researcher at the University of St. Andrews Scotland, UK.
July 1994: Degree with first class honors in "Biological Sciences", Developmental Biology major. University of Pisa
Invited speaker at (last five years):
-International Conference IMBP, Dresden, Germany. "Extrinsic and intrinsic cues in neoblast biology" (2013).
-International Master Course Human Pathology- Model organisms, University of Marseille, France. Model systems for in vivo studies of cell proliferation and differentation (2012).
-International Master Course Human Pathology- Model organisms, Università di Marseille, France. Planarians: a model system for in vivo studies of biological processes (2011).
-IFR48/URMITE, CNRS Marsiglia, Francia. Stem cells and tissue regeneration: the planarian toolbox (2011).
-International Conference IMBP, Munster, Germany." Role of RbAp48 and PHB 1 in neoblast biology" (2010).
-International Conference 22° Pasteur-Weizman symposium, Roma (Italy). Adult stem cells and tissue regeneration: in vivo investigations using planarians as model system (2010).
- Accademia Nazionale dei Lincei. 36° Seminario sulla evoluzione Biologica e i grandi problemi della biologia: le biotecnologie, le molecole, le cellule , gli organismi. I meccanismi rigenerativi e la loro evoluzione (2009).
- International conference Stem cells in tissue homeostasis, repair and cell therapy Università la Sapienza- Accademia Nazionale dei Lincei Roma, (Italy) Stem cells and regeneration: the planarian system (2008).
SELECTED PUBLICATIONS (Last 6 years)
1 Chelli* B, Salvetti* A, Da Pozzo E, Rechichi M, Spinetti F, Rossi L, Costa B, Lena A, Rainaldi G, Scatena F, Vanacore R, Gremigni V, Martini C. (2008). PK 11195 differentially affects cell survival in human wild-type and 18 kDa translocator protein-silenced ADF astrocytoma cells. J Cell Biochem. 105:712-123. IF: 3.122
2 Rechichi M, Salvetti A, Chelli B, Costa B, Da Pozzo E, Spinetti F, Lena A, Evangelista M, Rainaldi G, Martini C, Gremigni V, Rossi L. (2008). TSPO over-expression increases motility, transmigration and proliferation properties of C6 rat glioma cells. Biochim Biophys Acta. 1782:118-125. IF: 5.211
3 Rossi L., Salvetti A., Batistoni R., Deri P., Gremigni V. Planarians, a tale of stem cells. 2008. Cell Mol Life Science. 65:16-23. IF: 6,090
4 Salvetti A, Rossi L, Bonuccelli L, Lena A, Pugliesi C, Rainaldi G, Evangelista M, Gremigni V. (2009). Adult stem cell plasticity: neoblast repopulation in non-lethally irradiated planarians. Dev Biol. 328:305-314. IF: 4.094
5 Lena A, Rechichi M, Salvetti A, Bartoli B, Vecchio D, Scarcelli V, Amoroso R, Benvenuti L, Gagliardi R, Gremigni V, Rossi L. (2009). Drugs targeting the mitochondrial pore act as cytotoxic and cytostatic agents in temozolomide-resistant glioma cells. J Transl Med. 7:13. IF: 3.508
6 Bonuccelli L, Rossi L, Lena A, Scarcelli V, Rainaldi G, Evangelista M, Iacopetti P, Gremigni V, Salvetti A (2010). An RbAp48-like gene regulates adult stem cells in planarians. J Cell Sci. 123: 690-698. IF: 6.290
7 Backovic A., Cervelli T., Salvetti A., Zentilin L., Giacca M., Galli A. (2012). Cap