Sede ufficiale: VIA LUCA GHINI 13, 56126 PISA
Email: federica.gemignani@unipi.it
Telefono: 050 2211529
Sito web: http://www.unipi.it
Profilo
Ruolo:
Professoressa Ordinaria
Education:
Ph.D, in Microbiology and Genetics,University of Pisa
Specialist in Applied Genetics, University of Pisa
Academic Appointments:
2022- : Full Professor, Department of Biology, Genetics, University of Pisa.
2007-2022: Associate Professor, Department of Biology, Genetics, University of Pisa.
2006-2007: Researcher, Department of Biology, Genetics, University of Pisa.
2003-2006: Contract Professor Rientro dei Cervelli, (Ministry of Research and University),
Department of Biology, University of Pisa.
Other appointments and honors:
2002-2003: Research Assistant, International Agency for Research on Cancer (IARC), Lyon- France. IASLC-
CRFA (International Association of the Study of Lung Cancer - Cancer Research Foundation of
America) fellowship.
2000-2002: STA (Special Training Award) IARC, Lyon, Fance
1998-2000: Visiting scientist, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina, USA.
Recent and current grant supports:
2022-2026 AIRC (Associazione Itliana Ricerca sul Cancro)"Mesothelin and beyond: novel biomarkers and therapeutic tools in the fight of malignant pleural mesothelioma".
PI:F.Gemignani 01/01/22-31/12/26
2013-2015 ITT (Tuscan Tumor Institute)"Detection of novel genetic loci involved in the carcinogenesis of
differentiated thyroid carcinoma(DTC), following a genome-wide association study (GWAS)".
PI:F.Gemignani 07/05/13-06/05/15
2010-2012 PRIN (Research Projects for National Interest) Genetic susceptibility to non-medullary
thyroid carcinoma and benign nodular thyroid disease.
PI:F.Gemignani 23/09/10-22/09/12
2006-2008 R03 CA115062 (Small Grant Program, NIH, USA) Micro-array-based genotyping for studying
susceptibility to mesothelioma PI:S.Landi, Co-Investigator: F.Gemignani
2003-2006 MIUR Rientro dei Cervelli (Ministry of Research and University), "Development of microarray-
based genotyping of polymorphisms associated to myeloma and to the efficacy and adverse
effects of related chemotherapy" University of Pisa.
PI:F.Gemignani 01/10/03-30/09/06
Patents:
Patent n. TO2007A000148 del 28/02/2007 Dispositivo Microarray e procedimento per la rilevazione e identificazione di patogeni fungini (University of Pisa).
Academic teaching activities:
https://unimap.unipi.it/registri/registri.php?ri=011374&tmplt=principale.tpl&aa=2022
Struttura: Dipartimento di Biologia
Settore scientifico-disciplinare: Genetica BIOS-14/A
Cariche
- Presidente del Consiglio Aggregato - Biologia Marina (Laurea Magistrale)
- Presidente del Consiglio Aggregato - Conservazione ed Evoluzione (Laurea)
- Presidente del Consiglio Aggregato - Scienze Biologiche (Laurea)
- Presidente del Consiglio Aggregato - Conservazione ed Evoluzione (Laurea Magistrale)
- Presidente del Consiglio Aggregato - Neuroscience (Laurea)
- Presidente del Consiglio Aggregato - Biologia Applicata alla Biomedicina (Laurea Magistrale)
- Presidente del Consiglio Aggregato - Biologia Applicata alla Biomedicina (Laurea)
- Presidente del Consiglio Aggregato - Biologia Molecolare e Cellulare (Laurea Magistrale)
- Presidente del Consiglio Aggregato - Scienze Biologiche
- Presidente del Consiglio Aggregato - Biologia Marina (Laurea)
- Presidente del Consiglio Aggregato - Biologia Molecolare e Cellulare (Laurea)
Education:
Ph.D, in Microbiology and Genetics,University of Pisa
Specialist in Applied Genetics, University of Pisa
Academic Appointments:
2022- : Full Professor, Department of Biology, Genetics, University of Pisa.
2007-2022: Associate Professor, Department of Biology, Genetics, University of Pisa.
2006-2007: Researcher, Department of Biology, Genetics, University of Pisa.
2003-2006: Contract Professor Rientro dei Cervelli, (Ministry of Research and University),
Department of Biology, University of Pisa.
Other appointments and honors:
2002-2003: Research Assistant, International Agency for Research on Cancer (IARC), Lyon- France. IASLC-
CRFA (International Association of the Study of Lung Cancer - Cancer Research Foundation of
America) fellowship.
2000-2002: STA (Special Training Award) IARC, Lyon, Fance
1998-2000: Visiting scientist, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina, USA.
Recent and current grant supports:
2022-2026 AIRC (Associazione Itliana Ricerca sul Cancro)"Mesothelin and beyond: novel biomarkers and therapeutic tools in the fight of malignant pleural mesothelioma".
PI:F.Gemignani 01/01/22-31/12/26
2013-2015 ITT (Tuscan Tumor Institute)"Detection of novel genetic loci involved in the carcinogenesis of
differentiated thyroid carcinoma(DTC), following a genome-wide association study (GWAS)".
PI:F.Gemignani 07/05/13-06/05/15
2010-2012 PRIN (Research Projects for National Interest) Genetic susceptibility to non-medullary
thyroid carcinoma and benign nodular thyroid disease.
PI:F.Gemignani 23/09/10-22/09/12
2006-2008 R03 CA115062 (Small Grant Program, NIH, USA) Micro-array-based genotyping for studying
susceptibility to mesothelioma PI:S.Landi, Co-Investigator: F.Gemignani
2003-2006 MIUR Rientro dei Cervelli (Ministry of Research and University), "Development of microarray-
based genotyping of polymorphisms associated to myeloma and to the efficacy and adverse
effects of related chemotherapy" University of Pisa.
PI:F.Gemignani 01/10/03-30/09/06
Patents:
Patent n. TO2007A000148 del 28/02/2007 Dispositivo Microarray e procedimento per la rilevazione e identificazione di patogeni fungini (University of Pisa).
Academic teaching activities:
https://unimap.unipi.it/registri/registri.php?ri=011374&tmplt=principale.tpl&aa=2022
Didattica
Attività didattica
Incarichi di responsabilità didattica di moduli/insegnamenti
- Genomica (modulo dell'insegnamento genetica e genomica cod. 379ee) per Laurea in Biotecnologie
- Genetica umana (cod. 166EE) per Laurea Magistrale in Biologia applicata alla biomedicina
Ricevimento
Modalità: Tutti i giorni, a richiesta, previo appuntamento per e-mail
Ricerca
Pubblicazioni
- Genetically determined telomere length in monoclonal gammopathy of undetermined significance, multiple myeloma risk and outcome (Giaccherini, Matteo; Clay-Gilmour, Alyssa I; Liotti, Romano; Macauda, Angelica; Gentiluomo, Manuel; Brown, Elizabeth E; Machiela, Mitchell J; Chanock, Stephen J; Hildebrandt, Michelle A T; Norman, Aaron D; Manasanch, Elisabet; Rajkumar, S Vincent; Hofmann, Jonathan N; Berndt, Sonja I; Bhatti, Parveen; Giles, Graham G; Ziv, Elad; Kumar, Shaji K; Camp, Nicola J; Cozen, Wendy; Slager, Susan L; Canzian, Federico; Gemignani, Federica; Vachon, Celine M; Campa, Daniele - 2024 - 1.1 Articolo in rivista)
- BAG2, MAD2L1, and MDK are cancer-driver genes and candidate targets for novel therapies in malignant pleural mesothelioma (Bisceglia, Luisa; Morani, Federica; Guerrieri, Lara; Santoni-Rugiu, Eric; Çakilkaya, Pinar; Scatena, Cristian; Scarpitta, Rosa; Engelholm, Lars H.; Behrendt, Niels; Gemignani, Federica; Landi, Stefano - 2024 - 1.1 Articolo in rivista)
- Comparative analysis of genetic variants in pleural fluids and solid tissue biopsies of pleural mesothelioma patients: Implications for molecular heterogeneity assessment (Silvestri, Roberto; Rea, Filomena; Vitiello, Marianna; Moretti, Gabriele; Aprile, Vittorio; Lucchi, Marco; Aretini, Paolo; Mazzanti, CHIARA MARIA; Landi, Stefano; Gemignani, Federica - 2024 - 1.1 Articolo in rivista)
- Polymorphism Pro64His within galectin-3 has functional consequences at proteome level in thyroid cells (Silvestri, Roberto; Zallocco, Lorenzo; Corrado, Alda; Ronci, Maurizio; Aceto, Romina; Ricci, Benedetta; Cipollini, Monica; Dell'Anno, Irene; De Simone, Chiara; De Marco, Giuseppina; Ferrarini, Eleonora; Beghelli, Daniela; Mazzoni, Maria Rosa; Lucacchini, Antonio; Gemignani, Federica; Giusti, Laura; Landi, Stefano - 2024 - 1.1 Articolo in rivista)
- The breast cancer tumor microenvironment and precision medicine: immunogenicity and conditions favoring response to immunotherapy (Nicolini, Andrea; Ferrari, Paola; Silvestri, Roberto; Gemignani, Federica - 2024 - 1.1 Articolo in rivista)
- Strategies for single base gene editing in an immortalized human cell line by CRISPR/Cas9 technology (Corrado, Alda; Aceto, Romina; Miglietta, Simona; Silvestri, Roberto; Dell'Anno, Irene; Lepori, Irene; Ricci, Benedetta; Romei, Cristina; Giovannoni, Roberto; Poliseno, Laura; Evangelista, Monica; Vitiello, Marianna; Cipollini, Monica; Elisei, Rossella; Landi, Stefano; Gemignani, Federica - 2024 - 1.1 Articolo in rivista)
- The involvement of Purkinje cells in progressive myoclonic epilepsy: Focus on neuronal ceroid lipofuscinosis (Bernardi, Sara; Gemignani, Federica; Marchese, Maria - 2023 - 1.1 Articolo in rivista)
- A pleiotropic variant in DNAJB4 is associated with multiple myeloma risk (Dicanio, Marco; Giaccherini, Matteo; Clay-Gilmour, Alyssa; Macauda, Angelica; Sainz, Juan; Machiela, Mitchell J; Rybicka-Ramos, Malwina; Norman, Aaron D; Tyczynska, Agata; Chanock, Stephen J; Barington, Torben; Kumar, Shaji K; Bhatti, Parveen; Cozen, Wendy; Brown, Elizabeth E; Suska, Anna; Haastrup, Eva K; Orlowski, Robert Z; Dudzinski, Marek; Garcia-Sanz, Ramon; Kruszewski, Marcin; Martinez-Lopez, Joaquin; Beider, Katia; Iskierka-Jazdzewska, Elzbieta; Pelosini, Matteo; Berndt, Sonja I; Razny, Malgorzata; Jamroziak, Krzysztof; Rajkumar, S Vincent; Jurczyszyn, Artur; Vangsted, Annette Juul; Collado, Pilar Garrido; Vogel, Ulla; Hofmann, Jonathan N; Petrini, Mario; Butrym, Aleksandra; Slager, Susan L; Ziv, Elad; Subocz, Edyta; Giles, Graham G; Andersen, Niels Frost; Mazur, Grzegorz; Watek, Marzena; Lesueur, Fabienne; Hildebrandt, Michelle A T; Zawirska, Daria; Ebbesen, Lene Hyldahl; Marques, Herlander; Gemignani, Federica; Dumontet, Charles; Várkonyi, Judit; Buda, Gabriele; Nagler, Arnon; Druzd-Sitek, Agnieszka; Wu, Xifeng; Kadar, Katalin; Camp, Nicola J; Grzasko, Norbert; Waller, Rosalie G; Vachon, Celine; Canzian, Federico; Campa, Daniele - 2023 - 1.1 Articolo in rivista)
- A Drug Screening Revealed Novel Potential Agents against Malignant Pleural Mesothelioma (Dell'Anno, I.; Melani, A.; Martin, S. A.; Barbarino, M.; Silvestri, R.; Cipollini, M.; Giordano, A.; Mutti, L.; Nicolini, A.; Luzzi, L.; Aiello, R.; Gemignani, F.; Landi, S. - 2022 - 1.1 Articolo in rivista)
- Genetic signature of differentiated thyroid carcinoma susceptibility: a machine learning approach (Brigante, Giulia; Lazzaretti, Clara; Paradiso, Elia; Nuzzo, Federico; Sitti, Martina; Tüttelmann, Frank; Moretti, Gabriele; Silvestri, Roberto; Gemignani, Federica; Försti, Asta; Hemminki, Kari; Elisei, Rossella; Romei, Cristina; Zizzi, Eric Adriano; Deriu, Marco Agostino; Simoni, Manuela; Landi, Stefano; Casarini, Livio - 2022 - 1.1 Articolo in rivista)