Professoressa Associata – Dipartimento di Biologia | Tel.: ufficio 050 2211484, lab 0502211536 – Email: michela.ori@unipi.it<\/p>\n","protected":false},"template":"","meta":{"unipi-persone-chiave":"2520","unipi-persone-nome":"Michela","unipi-persone-cognome":"Ori","unipi-persone-email":"michela.ori@unipi.it","unipi-persone-cv":"Present position\tAssociate Professor in Cellular and Developmental Biology
\r\n ORCID ID: 0000-0002-6777-0208
\r\n SCOPUS ID: 6701837889
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\r\nRESEARCH INTERESTS: Developmental neurobiology using Danio rerio (zebrafish) as model systems: generation and functional studies of animal models for translational research in the field of neurodevelopmental disorders. Using the most recent biothecnologies such as CRISPR\/Cas9, CRISPR\/Cas13 and Base editors we are generating new in vivo models for Pitt-Hopkins syndrome, a rare genetic neurodevelopmental disorder with the support of Fondazione Telethon and Associazione Italiana Sindrome di Pitt-Hopkins. In parallel we are studying the developmental function of other genes, PTBP1, NKT and ZNF865, found mutated in human orphan genetic disorders. The ambition of our lab is to contribute to developmental biology unveiling new molecular mechanisms involved in brain development and to use our expertise in neurodevelopment to propose new possible therapeutic strategies aimed to ameliorate patients life.
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\r\nEDUCATION AND TRAINING\t
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\r\n-07\/03\/1997 Graduation (Laurea) 110\/110 cum laude in Molecular and Cellular Biology, University of Pisa
\r\n-January 2001, PhD defense. Mention: Exellent. Thesis: Functional role of the homeotic gene Hoxa2 during the cranial neural crest development using the Xenopus laevis as animal model. Supervisor: Prof. Irma Nardi, University of Pisa and Prof. F.M. Rijli IGBMC Institute, Strasbourg, France
\r\n\u2013Practical Courses and Master : Cell & Developmental Biology of Xenopus Cold Spring Harbor Laboratory (CSHL, New York, USA) 1999 - granted fellowship
\r\n\u2013Practical Course \"Animal models for Development and Disease\u201d University of Sheffield, Sheffield, UK European Molecular Biology Organization\" (EMBO) 2004
\r\n-Course: \"Zebrafish: an animal model in biomedical research\", International Workshop, King\u2019s College London - UK 2013
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\r\nPREVIOUS POSITIONS
\r\nNov. 01-Gen.02 Post doctoralFellowship \"Development Travel Fellowship\" Prof. F.M. Rijli\u2019s Lab. IGBMC, Strasbourg, France.
\r\n2001-2005 Postdoctoral Fellowship (Assegno di Ricerca) Department of Physiology and Biochemistry University of Pisa.
\r\n2005-2008 Young Group Leader position \u201cRicercatore in Formazione\u201d, Department of Biology, University of Pisa
\r\n2008- 2014 Assistant Professor, Department of Biology, University of Pisa
\r\n2014- Associate Professor Department of Biology, University of Pisa
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\r\nAwards\t2001: Development Travelling Fellowship to spend a working period in the Laboratory of prof. F.M. Rijli, Institute of Biologique et Genetique Molecoulaire, (IGBMC) Strasbourg, France
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\r\n2011: Prize \u201cYoung Researchers\u201d University of Pisa
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\r\nTEACHING ACTIVITIES
\r\n2014-: Advanced Course in Cell Biology for Master students in Cellular and Molecular Biology and students in Biomedicine, University of Pisa
\r\n2019- : Development and Differentiation of the Nervous System for Master students in Neuroscience, University of Pisa
\r\n2020- : Amimal experimentation and alternative methods: the 3Rs for Master students in Cellular and Molecular Biology and students in Biomedicine and Neuroscience University of Pisa
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\r\n2015-2019: Cytology and Histology Course for bachelor students in Biological Sciences
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\r\nINSTITUTIONAL RESPONSIBILITIES -Member of the steering committee of the Gei-Societ\u00e0 Italiana di Biologia dello Sviluppo e della Cellula (Italian society for Cellular and Developmental Biology) -Member of the steering committee of \"Centro 3R\" (Italian inter-university center for the promotion of the 3Rs in teaching and research). -Member of the board for the PhD in Biology, University of Pisa - Member of the permanent committee for the bachelor Degree in Biological Sciences, University of Pisa
\r\n-Delegate for Department of Biology for students with learning disabilities (DSA)- Delegate for Department of Biology for Sustainability (CoSa).","unipi-persone-link-esterno-cv":"","unipi-persone-modalita-ricevimento":"Qualsisi giorno su appuntamento preso via email","unipi-persone-luogo-ricevimento":"","unipi-persone-ore-ricevimento":"","unipi-persone-telefono":"ufficio 050 2211484, lab 0502211536","unipi-persone-sitoweb":"http:\/\/www.biologia.unipi.it\/","unipi-persone-cariche":"","unipi-persone-link-orario-lezioni":"https:\/\/unipi.prod.up.cineca.it\/calendarioPubblico\/matricola=080210","unipi-persone-link-registro-lezioni":"https:\/\/unimap.unipi.it\/registri\/registri.php?ri=080210&tmplt=principale.tpl","unipi-persone-settore-scientifico":"Anatomia, Biologia Cellulare e Biologia Dello Sviluppo Comparate BIOS-04\/A","unipi-persone-ruolo":"Professoressa Associata","unipi-persone-arpi":"https:\/\/arpi.unipi.it\/cris\/rp\/rp13797","unipi-persone-pubblicazioni":"